Membrane Biology: Fission behind BARs
نویسنده
چکیده
Membrane bending is accomplished in part by amphipathic helix insertion into the bilayer and the assembly of BAR domain scaffolds preparing the membrane for fission. Two recent studies highlight the roles of amphipathic helices and BAR scaffolds in membrane fission and establish the structural basis of membrane bending by the N-BAR protein endophilin.
منابع مشابه
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ristina Hidalgo Carcedo, Alberto Luini, Daniela Corda, and colleagues (Consorzio Mario Negri Sud, Santa Maria Imbaro, Italy) suggest that Golgi membranes are chopped up by a protein called BARS before mitosis can occur. Their cell culture studies contrast, however, with results from genetic knock-out experiments. BARS is closely related to the CtBP family of transcriptional repressors needed fo...
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ristina Hidalgo Carcedo, Alberto Luini, Daniela Corda, and colleagues (Consorzio Mario Negri Sud, Santa Maria Imbaro, Italy) suggest that Golgi membranes are chopped up by a protein called BARS before mitosis can occur. Their cell culture studies contrast, however, with results from genetic knock-out experiments. BARS is closely related to the CtBP family of transcriptional repressors needed fo...
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ورودعنوان ژورنال:
- Current Biology
دوره 22 شماره
صفحات -
تاریخ انتشار 2012